Vaccination is the best protection against meningococcal serogroup B infections and their complications. For instance, meningitis that is an infection of the brain lining and meningococcemia that is an infection of the blood are 2 serious infections caused by serogroup B meningococcus

There are different serogroups or types of meningococcus, among other serogroups A, B, C, Y and W135. This vaccine protects against serogroup B. 

The vaccine is recommended for persons with a high risk of infection from meningococcus.


Some symptoms may be caused by the vaccine, e.g. redness at the injection site. Other problems may occur by chance and are not related to the vaccine, e.g. cold, gastro, headache.

Meningococcal serogroup B vaccine is safe. Most reactions are harmless and do not last long.

The Nature and Frequency of Known Reactions to Vaccine
FrequencyKnown reactions to this vaccine

In most cases
(more than 50% of people)

  • Pain, redness and swelling at the injection site in children under 10
  • Fever (≥ 38 °C), unusual crying, loss of appetite, irritability, drowsiness (sleepiness), vomiting and diarrhea in children under 2

Very often
(less than 50% of people)

  • Pain, redness and swelling at the injection site in teenagers from ages 11 to 18
  • Headache in teenagers from ages 11 to 18

What to Do after Vaccination

Tips to follow immediately following vaccination

Wait 15 minutes before leaving premises where vaccine is received. If an allergic reaction occurs, the symptoms will appear a few minutes after the vaccination.

If you feel side effects, immediately inform the person giving the vaccine. That person will be able to treat you immediately.

Tips to follow at home

If you experience redness, pain or swelling at the injection site, apply a cold, damp compress on it.

Use medication for fever or discomfort if needed.

For children under 2, give acetaminophen as soon as possible after vaccination, and then every 4 to 6 hours for the first 12 hours.

When to Seek Medical Help

See a doctor if one of the following applies to you: 

  • You experience serious and unusual symptoms
  • Your symptoms get worse instead of improving
  • Your symptoms last over 48 hours