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Combined tetanus, diphtheria, pertussis (whooping cough) and polio vaccine (Tdap-IPV) – 4 years of age and older


Vaccination is the best protection against these diseases and their complications:

According to Québec’s immunization schedule, children are given one dose of Tdap-IPV vaccine before they start school. The vaccine can also be given to children over 4 years of age and adults who need protection against these 4 diseases.

For babies and children under 4 years of age, another combined diphtheria, tetanus, pertussis and polio vaccine is available. To find out more about this other vaccine, go to the page Combined diphtheria, tetanus, pertussis (whooping cough) and polio vaccine (DTaP-IPV) – Under 4 years of age.


Some symptoms may be caused by the vaccine, e.g. redness at the injection site. Other problems may occur by chance and are not related to the vaccine, e.g. cold, gastro, headache.

Tdap-IPV vaccine is safe. Most reactions are harmless and do not last long.

The nature and frequency of possible reactions to vaccine
FrequencyPossible reaction to the vaccine

In most cases
(more than 50% of people)

  • Pain at the injection site
  • Fatigue, headache

Very often
(less than 50% of people)

  • Redness and swelling at the injection site
  • Discomfort, dizziness, nausea, diarrhea, shivering

(less than 10% of people)

  • Fever
  • Loss of appetite, vomiting
  • Irritability, drowsiness (sleepiness)
  • Skin rash
  • Swollen lymph nodes

(less than 1% of people)

  • Small lump for a few weeks at the injection site

Very rarely
(less than 1 person in 10,000)

  • Sterile abscess at the injection site
  • Intense pain and weakness in the arm for several weeks

What to do after vaccination

Tips to follow immediately following vaccination

Wait 15 minutes before leaving premises where vaccine is received. If an allergic reaction occurs, the symptoms will appear a few minutes after the vaccination.

If you feel side effects, immediately inform the person giving the vaccine. That person will be able to treat you immediately.

Tips to follow at home

If you experience redness, pain or swelling at the injection site, apply a cold, damp compress on it.

Use medication for fever or discomfort if needed.

When to seek medical help

See a doctor if one of the following applies to you:

  • You experience serious and unusual symptoms
  • Your symptoms get worse instead of improving
  • Your symptoms last over 48 hours

Last update: April 17, 2019


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